O Efeito Do Uso De Probióticos No Controle E Tratamento Da Diabetes Mellitus Tipo 2: Uma Revisão Sistemática

Abstract

Introducion: Type 2 Diabetes Mellitus (DM2) is a chronic diasease that has many complications if not controlled and treated properly. Generally, the diasease develops in adulthood, and its possible causes are directly intertwined with lifestyle and risk factors, such as obesity, inadequate nutrition, hypertension, and sedentary lifestyle. New therapeutic approaches are being addressed. Recent research demonstrates that therapy with probiotcs is capable of generating nutricional benefits in maintaining the body and controlling certain diseases when administered in adequate amounts. Objective: The main objective of this study was to evaluate, in clinical trials, the effectiveness of probiotic suplementation in the control and treatment of DM2. Methods: The search for information was carrid out in the indexed databases: Google academic PubMed, Science direct and virtual health library of the (VHL). The filters used were: studies published in the last 10 years, in humans and adults aged 18 years and over. Results: Fourteen randomized studies that showed significant improvements in fasting glucose, glucated hemoglobin and HOMA-IR (insulin resistence) were selected. Beneficial effects were also observed on the lipid profile, and oxidative stress, on some inflamatory markers and also on bacterial translocation. Conclusion: The systematic review with randomized studies pointed out that the use of probiotcs in the diet of individuals with DM2 can be used therapeutically to control and treat the disease.