Benzodiazepínicos: propriedades farmacológicas, uso, abuso e dependência

Abstract

Due to their ability to depress the CNS, acting in a sedative-hypnoticway, benzodiazepines are widely used globally for anxiety disorders and rarely, with off-label indication. Even with therapeutic purposes, it is observed that these medications without due caution in performing weaning, lack of programming to reduce the period of use through planning and indiscriminate renewal of prescriptions in patients who use chronically, end uppresenting adverse effects, physical and psychological dependence. The lack of knowledge about the a fore mentioned drug class, indiscriminate use and lack of professional preparation, whether by a psychiatrist or general practitioner, end supcontributing as an aggravating factor and perpetuating element of the use, abuse and dependence on the part of users of the Public Health System, especially. To compose this work, we used a narrative review of some publications present in data from Pubmed, Academic Google, Scielo, Virtual Health Library (VHL), Data base of the Primary Care In formation System. The DeCS (Health Science Descriptors) Platform was used and the following research descriptors were defined: “psychiatry”, “Substance Use Disorders”. Given the above, this study uses a literature review regarding the pharmacological properties, use, abuse and dependence of this class of drugs, pointing out the need to apply educational and therapeutic measures at the national level to rationalize the use of benzodizepines, minimizing adverse effects and the possibility/probability of dependence due to indiscriminate use and abuse.