A CORRELAÇÃO ENTRE O USO INDISCRIMINADO DE ANTIBIÓTICOS E INFECÇÕES POR Mycobacterium tuberculosis: UMA REVISÃO INTEGRATIVA

Abstract

The inappropriate and excessive use of antibiotics is closely linked to the lack of compliance with therapeutic protocols, which is one of the main factors contributing to the development of resistant strains. Additionally, concerns about increased antibiotics prescriptions, interruption of treatment for other conditions, and the potential consequences of bacterial resistance have become more evident during the COVID19 pandemic. This study aimed to investigate whether there is a correlation with the uncontrolled use of antibiotics in Mycobacterium tuberculosis infections to raise awareness among the population about the adverse implications related to the indiscriminate use of antibiotics for tuberculosis treatment. The study also aims to explore therapeutic perspectives that can be employed in cases of resistance. As for the methodology, it involves an integrative literature review with a qualitative and descriptive approach conducted through articles and journals available in the databases of the United States National Library of Medicine (PubMed), Web of Science, and Scientific Electronic Library Online (SciELO). Health Descriptors (DeCs) such as Mycobacterium tuberculosis, tuberculosis, indiscriminate use, antibiotics , excessive utilization, and self-medication were used. The results highlighted that the relationship between prolonged antibiotic use and the emergence of Mycobacterium tuberculosis infections is not only true but also underscores the urgent need for more stringent methods in drug prescription to avoid complications due to antibiotics - resistant bacteria.